Wednesday April 18
    
     7:15 – 8:00 Breakfast
    
     8:00 – 10:00 Slide session 1:
    
     Intercellular compartmentation of brain energy metabolism
    
     1. Pierre Magistretti (Switzerland) Astrocyte-derived lactate and brain cognitive function
    
     2. Gerald Dienel (USA) Metabolite tracking through glial syncitium and brain ECF.
    
     3. Helle Waagepetersen (Denmark) Regulation of GABA and glutamate shuttles
    
     4. Silvia Mangia (USA) Lactate shuttle from neurons to astrocytes.
    
    5. Bill Shuttleworth (USA) Effects of astrocyte glycogen on cortical spreading depression

10:30 – 12:30 Slide session 2:
    
     Normal and abnormal mitochondrial function
    
     1. Verdin E (USA) Sirtuin regulation of mitochondria: energy production， apoptosis， and signaling.
    
     2. Starkov A (USA) Metabolism-dependent free radical scavenging by mitochondria
    
     3. Richard Youle (USA) Mitochondria quality control in hereditary Parkinson’s disease.
    
     4. Vera Adam-Vizi (Hungary) KGDH mutations， mitochondrial dysfunction， and neurological disease
    
     5. Michael Duchen (UK) Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations.
    
    
    
     12:30 – 13:30 Lunch
    
     13:30 - 15:00 Point / Counterpoint Forum 1:
    
     How does mitochondrial dysfunction lead to neuronal death: the relative roles of oxidative stress， energy failure， and apoptosis.
    
     Moderator: Anne Murphy (USA) - Presenters: David Nicholls (Sweden)， and Flint Beal (USA)
    
     15:30 - 17:30 Student /fellow data blitz by travel stipend awardees
    
     18:00 - 19:00 Dinner
    
     19:30 – 21:30 Poster session 1

Thursday April 19
    
     7:15 – 8:00 Breakfast
    
     8:00 - 10:00 Slide session 2:
    
     Emerging technologies for measuring brain energetics
    
     1. L. Felipe Barros (Chile) - Single-cell measures of glucose utilization in situ.
    
     2. Akos Gerenscer (Hungary) - Measures of in situ mitochondrial function.
    
     3. Rolf Greutter (Switzerland) - MRS measures glycogen & glucose metabolism in vivo.
    
     4. Tim Murphy， (Canada) - Use of voltage-sensitive dyes in vivo.
    
     5. Bruno Weber (Switzerland) - Multimodal in vivo investigations of brain energetics.

10:30 – 12:30 Slide session 3:
    
     Effects of aging and disease on brain energetics
    
     1. Kevin Behar (USA) Aging brain mitochondria as assessed by MRS. .
    
     2. Alicia Kowaltowski (Brazil) Caloric restriction， mitochondrial function， and aging brain. .
    
     3. Martin Brand (USA) A systems biology approach to aging brain metabolism.
    
     4. Emanuel Brouillet (France) Mitochondrial dysfunction in neurodegenerative disorders.
    
     5. Jorge A Oliveira (Portugal) Mitochondrial abnormalities in Huntington’s disease

12:30 – 13:30 Lunch
    
     13:30 – 16:00 Open
    
     16:00 – 18:00 Poster Session 2
    
     19:00 – 21:00 Reception and Plenary Lecture at the Monterey Aquarium Chair: Bruce Ransom
    
     Brian Mac Vicar (Canada) Dynamic interplay between local cerebral blood flow， energy metabolism， and neural function， and the consequences its disruption.

Friday April 20
    
     7:15 – 8:00 Breakfast
    
     8:00 - 10:00 Slide session 5
    
     Energetics of neurological disorders (Part 2)
    
     1. Fernando Bozza (Brazil) Effects of systemic inflammation on brain energetics.
    
     2. Andreas Plaitakis (Greece) Glutamate dehydrogenase in Parkinsons Disease and other neurological disorders
    
     3. Avtar Roopra (USA) A The energy sensor AMPK modulates neuronal plasticity: therapeutic possibilities.
    
     4. Susanna Scafidi (USA) Disturbances in oxidative metabolism after brain trauma.
    
     5. Raj Ratan (USA) HIF1， and epigenetic regulation in vascular dementia and stroke.
    
    6. Louise McCullough (USA) AMP kinase in cerebral ischemia.